A significantly lower concentration of Ki-67 was observed in the OSCC cancer subtype compared with the joint group of OPSCC with HPSCC and LSCC cancer subtypes (0.0005 (0.0002–0.0017) vs. 0.0032 (0.0014–0.0047); p = 0.0128) in the tumor samples. This evidence concerns the gene MKI67 and cancer.