However, a positive correlation was observed between the CDKN2A protein level in the tumor samples and the smoking years (0.29; p = 0.0376), while the margin samples showed a correlation with the number of cigarettes smoked per day (0.30; p = 0.0363) and a medium positive correlation with pack-years (0.31; p = 0.0367). Here, CDKN2A is linked to neoplasm.