GLS and breast carcinoma: Indeed, CPT1 and glutaminase (GLS)-mediated Angiopoietin-like protein (ANGPTL4)-induced energy metabolism and cell proliferation in non-small cell lung cancer (NSCLC) cells [45], whereas the simultaneous inhibition of CPT1 and GLS enhanced the suppression of proliferation and migration of CB-839-resistant breast cancer cells [46].