Table 1 provides a concise summary of the anti-tumor effects of Dectin-1 in melanoma, breast cancer, and multiple myeloma, as well as its pro-tumor effects in pancreatic ductal adenocarcinoma, colorectal cancer, gastric cancer, renal clear cell carcinoma, and lung adenocarcinoma, along with the underlying mechanisms involved. The gene discussed is CLEC7A; the disease is AL amyloidosis.