The AUC values for clinically significant PCa predictions are as follows: PSA, 0.574 [95% CI: 0.330–0.819]; ultrasound imaging, 0.708 (95% CI: 0.508–0.908); T2WI, 0.803 (95% CI: 0.629–0.976); DWI, 0.564 (95% CI: 0.341–0.787); and ADC, 0.662 (95% CI: 0.449–0.874). The gene discussed is KLK3; the disease is posterior cortical atrophy.