Besides clinical parameters such as serum prostate-specific antigen (PSA) levels, multiparametric (mp) MRI, including T2-weighted (T2w) images; diffusion-weighted imaging (DWI); and dynamic contrast-enhanced (DCE) sequences have been established as a standard diagnostic workup in men at risk for PCa [7,8,9]. This evidence concerns the gene KLK3 and posterior cortical atrophy.