PGC-1α-high samples clustered well with SCLC-ASCL1 and PARCB-ASCL1 tumors (HC6), whereas PGC-1α-low samples clustered better with SCLC-POU2F3 and PARCB-POU2F3/ASCL2 tumors (HC5). The gene discussed is ASCL1; the disease is small cell lung carcinoma.