PF4V1 and type 2 diabetes mellitus: The analysis showed that 6 proteins, SHBG, APOD, IGFBP2, IGFBP6, cartilage oligomeric matrix protein (COMP), and platelet factor 4 variant 1 (PF4V1), were differentially expressed when both T2D-progressors and nonprogressors were healthy (Figure 4C).