In fact, Cybb was one of only 18 genes identified and ranked in the top 3 as a potential biomarker in gastric cancer in a recent study that utilized weighted gene co-expression network analysis and samples from The Cancer Genome Atlas (GEO, GSE13911).72 Additionally, studies in other cancer models suggest it is a potential therapeutic target.56,73,74. The gene discussed is CYBB; the disease is gastric cancer.