As shown in Figures 6B, D, the main author keywords included “tumor immune microenvironment”, “lipid metabolism reprogramming”, “circular RNA”, “exosome”, “prognostic model”, “immunotherapy”, “lipid metabolism”, “glycolysis”, “tumor microenvironment”, “Warburg effect”, “metformin”, “mitochondria”, “myc”, “pkm2”, “hif-1” and “hif”. Here, PKM is linked to neoplasm.