Our results showed that the percentage of CD38+CD4+ T cells were positively associated with C-reactive protein (CRP, r = 0.466, P = 0.025), while negative correlation with triglyceride (TG, r = -0.509, P = 0.011) and immunoglobulin A (IgA, r = -0.426, P = 0.048) in MDA5+ DM patients. This evidence concerns the gene CD38 and dermatomyositis.