However, in the tumor samples, significant negative correlations between FOXE1 mRNA and the methylation values of the three regions were observed (CpGisland2’ r = -0.164; 2-sites-CpGisland2’ r = 0.218; CpGisland1’ r = -0.095, P < 0.04), while no correlation was observed in the non-tumor samples. This evidence concerns the gene FOXE1 and neoplasm.