Thiazolidinediones (TZDs), a class of peroxisome proliferator-activated receptor gamma (PPARγ) agonist, is the inhibitor of the ferroptosis marker ACSL4 (110), and has been found to prevent ferroptosis in many tissues and models including acute kidney injury (111), a ferroptosis mouse model (112), lung I/R injury (113), and renal fibrosis (114). Here, PPARG is linked to acute kidney injury.