AKT1 and familial dilated cardiomyopathy: Sitagliptin was found to attenuate DCM by attenuating myocardial apoptosis, inflammation, and nitroxidative stress by targeting the liver kinase B1/AMPK/Protein kinase B (LKB-1/AMPK/Akt) and Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathways and promoting cardiomyocyte autophagy separately (105–107).