In the current study, after accounting for confounders including age, sex, blood pressure, BMI, TC, FBG, ALT, and AST, we discovered that every single-unit rise in the TG/HDL-C ratio was associated with a 37% increase in the likelihood of incident diabetes, aligning with studies from South Korea and Singaporean Chinese populations (19–22). The gene discussed is GPT; the disease is diabetes mellitus.