DDX41 and Zika virus infectious disease: Our in vitro and in vivo experimental results showed that the levels of JEV-neutralizing Abs induced by either Ad5-JEV-Emut or JEV-Emut mRNA-LNP did not decrease as compared with vaccine candidates encoding JEV-EWT, while the levels of Abs reactive to ZIKV antigen and its ADE effect on ZIKV infection were significantly reduced.