INS and cancer: The top 10 significantly enriched pathways include Glycerophospholipid metabolism, Choline metabolism in cancer, Insulin signaling pathway in cancer, Glycolysis/Gluconeogenesis, Central carbon metabolism in cancer, Alanine, aspartate and glutamate metabolism, Niacin and Niacinamide metabolism, β-Alanine metabolism, Insulin resistance, and the AMPK (AMP-activated protein kinase) signaling pathway (Figure 5B).