However, tubule‐specific deletion of Mydgf increased the levels of serum creatinine (SCr) and blood urea nitrogen (BUN, Figure 2b), exacerbated tubular atrophy and extracellular matrix deposition in mice with AAN, based on periodic acid‐Schiff (PAS) and Sirius Red staining (Figure 2c). Here, MYDGF is linked to Balkan nephropathy.