We also detected the amplification or gain of the YTHDF1 gene in a substantial proportion of samples from The Cancer Genome Atlas (TCGA) GC cohort (n = 410, 65.0%) and the Cancer Cell Line Encyclopedia (CCLE; all cell lines, n = 916, 14.2%; GC cell lines, n = 47, 14.9%) (Figure 1A). Here, YTHDF1 is linked to gastric cancer.