STAT1 and colorectal cancer: A previous study reported that the m6A methyltransferase Mettl3/14 complex regulates the Ifn‐γ–Stat1–Irf1 axis in mouse colorectal cancer models.[51] The proposed molecular mechanism involves the degradation of Stat1 and Irf1 mRNAs via Ythdf2, resulting in enhanced cancer immunity through the inhibition of RNA m6A modifications and the effect of Ythdf2.