IRF1 and cancer: RNA m6A modification plays a crucial role in the regulation of post‐transcriptional gene expression, and previous studies have emphasized the significant impact of RNA m6A modifications on cancer immunity.[23, 24, 25] In addition, a lower level of m6A modification is associated with increased immune infiltration and enhanced response to immunotherapy.[25] This study reveals the inhibitory roles of YTHDF paralogs, the m6A reader proteins, in cancer immunity related to GC by modulating the mRNA stability of IRF1, a key regulator of the IFN‐γ response.