IRF1 and cancer: Given that IRF1 serves as a master regulator of IFN‐γ responsiveness, governing diverse IFN‐γ signaling pathways, including those involved in anti‐cancer apoptotic pathways[36] and enhanced immunogenicity,[37] the regulation of IFN‐γ signaling serves as a fundamental molecular mechanism underlying the immune evasion effect of YTHDF1.