YTHDF1 has been reported to be upregulated in multiple cancer types, thereby promoting cancer growth.[26, 27, 28] Copy number amplification of YTHDF1 genes was identified as a genetic cause underlying the increased expression of YTHDF1 in tumor tissues, as demonstrated in both our in‐house GC and the TCGA GC cohorts. This evidence concerns the gene YTHDF1 and neoplasm.