As this patient progressed from a JAK2-mutant myeloproliferative neoplasm (MPN) or chronic myelomonocytic leukemia (CMML) to AML (Supplementary Table 1), this cell hints at the presence of residual MPN- or CMML-related blood cells at the time of CK-AML diagnosis. This evidence concerns the gene JAK2 and acute myeloid leukemia.