For example, our study identified a frequency of 47% of the GC IL-6 genotype and 30.8% of the GT genotype of COL1A1, in which both contained a heterozygous genotype, indicating that the population has a medium predisposition to musculoskeletal injuries, such as fractures, osteoporosis, and loss of muscle strength. The gene discussed is COL1A1; the disease is osteoporosis.