Multiple subunits of complex I show different expression characteristics in different cancer types; for example, NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 4‐Like 2 (NDUFA4L2) is overexpressed in colorectal cancer and clear cell renal cell carcinoma [145]. The gene discussed is COXFA4L2; the disease is clear cell renal carcinoma.