A study by Liu et al. revealed that baicalin significantly promotes pyroptosis in gastric cancer through the generation of ROS and the upregulation of NLRP3 and GSDMD-N expression; further research revealed that baicalin also increases the protein level of NF-κB and activates this pathway to trigger pyroptosis (Liu J. et al., 2024). The gene discussed is NFKB1; the disease is gastric cancer.