The results showed that ApoB (P < 0.001, OR 0.177, 95 % CI 0.080–0.394), LDL (P = 0.002, OR 0.699, 95 % CI 0.555–0.881), and TC (P < 0.001, OR 0.694, 95 % CI 0.569–0.847) reduced PD risk, and HCY (P < 0.001, OR 1.084, 95 % CI 1.049–1.120) conferred an aggravated risk of developing PD (Table 2). The gene discussed is APOB; the disease is Parkinson disease.