Regression analysis revealed statistically significant associations of MoCA with the duration of diabetes, HbA1c, and lipid parameters, with HbA1c being the largest contributor to cognitive decline at 60.66%, while the contributions of various lipid parameters were considerably lower (LDL: R2 = 0.092, VLDL: R2 = 0.067, total cholesterol: R2 = 0.167). The gene discussed is DOCK3; the disease is diabetes mellitus.