WBC: White blood cells; HG: Hemoglobin; PLT: platelet; HG-F: Fetal Hemoglobin; HCT: Hematocrit; ACS: acute chest syndrome; AVN- Avascular necrosis; VDD- Vitamin D deficiency; G6PD: glucose-6-phosphate dehydrogenase; 5 Alpha THAL trait: Alpha thalassemia trait. This evidence concerns the gene G6PD and vitamin D deficiency.