Promyelocytic leukaemia nuclear bodies (PML-NBs) are a ribosome containing a variety of proteins, which play an important role in many biological processes, including gene transcription, tumor suppression, apoptosis, neovascularization, DNA repair, antiviral response, and maintenance of genome stability (Bernardi and Pandolfi, 2007; de Thé et al., 2012). Here, PML is linked to acute promyelocytic leukemia.