PRR11 and familial pancreatic carcinoma: Pertinent data have shown that PRR11 is a candidate oncogene in mammals, often playing a vital role in the initiation and progression, as well as other carcinogenic processes of various solid tumors, such as hilar cholangiocarcinoma (4), lung cance (5,6), pancreatic cancer (7), osteosarcoma (8), gastric cancer (9), breast cancer (10,11), colorectal cancer (12), ovarian cancer (13) and cervical cancer (14).