A candidate for this might be BPAG2 (also known as collagen 17A1) which is known to bind, in the extracellular matrix, to ITG6A.16Biallelic mutations in BPAG2 also cause a JT-EB17associated with nail dystrophy, but we found no reports of pyloric atresia in the BPAG2 disorder. The gene discussed is COL17A1; the disease is Nail dystrophy.