For FGFR2 fusion/rearrangement in intrahepatic cholangiocarcinoma, consider treatment with pemigatinib, infigratinib, futibatinib, gunagratinib, etc. (FDA-approved for posterior treatment of unresectable, locally advanced, or metastatic intrahepatic cholangiocarcinoma, with pemigatinib approved for domestic marketing by NMPA). The gene discussed is FGFR2; the disease is intrahepatic cholangiocarcinoma.