At present, a cancer multi-gene panel testing of the female patient (source of KS-cSCC-1) revealed abnormalities in BAP1, CDKN2A, CDKN2B, MET, MTAP, MYC, RAD21, STK11, and TP53 genes, attentions will be paid to those genes first. The gene discussed is CDKN2B; the disease is cancer.