CYP3A4 and cystic fibrosis: KEGG analysis also identified that 4060, 4653, 4339,4184 and 4510 DEGs were involved in the pathway of “Biosynthesis of secondary metabolites (map01110)” in CF/CK, NF25/CK, NF50/CK, NF75/CK and NF100/CK groups, respectively.