The results of the univariate analyses showed that the mitotic index (P < 0.001), tumor size (P < 0.001), tumor site (P = 0.01), NIH risk category (P < 0.001), surgery (P = 0.028), adjuvant therapy (P = 0.003), CD34 (P = 0.003), DOG-1 (P = 0.001), Ki-67 (P < 0.001), RPR (HR = 0.334, 95% CI: 0.186–0.601, P < 0.001), PVPR (HR = 0.155, 95% CI: 0.066–0.360, P < 0.001), HPR (HR = 0.155, 95% CI: 0.066–0.360, P < 0.001), LWR (HR = 0.316, 95% CI: 0.183–0.548, P < 0.001), and SIRI (HR = 2.601, 95% CI: 1.445–4.682, P = 0.001) were remarkable predictors of RFS. Here, ANO1 is linked to neoplasm.