For example, ERCC1 and ERCC2 have been reported to be correlated with drug resistance in NSCLC (14, 15), ERCC2 controls the proliferation, migration and invasion of bladder cancer cells (16), elevated ERCC6 has been associated with drug resistance in colorectal cancer (17), and ERCC8 is involved in chemoresistance of esophageal cancer (18). Here, ERCC2 is linked to colorectal cancer.