The most significant methylation-expression associations included LGALS3BP, involved in intercellular interactions, cell cytotoxicity and upregulated during cancer and HIV infection in humans (Capone, Iacobelli, and Sala 2021; Lodermeyer et al. 2013), although its antiviral properties may not be fully conserved in macaques (Lodermeyer et al. 2018). The gene discussed is LGALS3BP; the disease is cancer.