Some of the 14 transcripts in our Ki67neg/lowCD44high T-ALL cell signature encode for markers implicated in cancer cell migration (MALAT1, Metastasis-associated lung adenocarcinoma transcript 1 [60]), immune checkpoints / tolerance (HLA-B/C/E, Human Leukocyte Antigen [61]), protein synthesis through the inhibition of rRNA processing (PNRC1, Proline-rich Nuclear Receptor Coactivator 1 [62]) and drug resistance (ARL4C, ADP ribosylation like factor 4 C [63]). The gene discussed is ARL4C; the disease is cancer.