In the human lung cancer xenograft model, DMH1, a small molecule inhibitor of BMP signaling, markedly diminished lung cell proliferation, induced cell death, and cell migration and invasion in NSCLC cells by inhibiting p-Smad1/5/8 signaling and down-regulating Id1, Id2, and Id3 (Hao et al. 2014). The gene discussed is ID1; the disease is lung carcinoma.