This effect of the hepatocyte-specific Dbi knockout correlated with reduced CORT-induced food intake (Fig. 3m) and weight gain (Fig. 3n), as well as the normalization of hepatomegaly, dyslipidaemia, insulin resistance, fasting plasma glucose and HOMA-IR values (Fig. 3o and Supplementary Fig. 5). Here, DBI is linked to inherited lipid metabolism disorder.