To determine whether the a09b08 ImmTAV molecule could also elicit T cell killing of targets via recognition of endogenously presented Env371-379 (L6I), PBMC were cocultured with PLC/PRF/5 (Ag+), an HCC cell line that expresses HBsAg from integrated HBV DNA (Supplementary Fig. 9)41–44. This evidence concerns the gene RENBP and hepatocellular carcinoma.