BLM and neoplasm: Noncore HRR mutations were identified in 11 tumors, including ATM (n = 4), FANCA (n = 2), RAD50 (n = 2), and 1 each of FAM175A, FANCC, and BLM. Co-occurring alterations were identified in two patients with one patient having both BRCA2 and ATM mutations and the other having both BRCA2 and FAM175A. Tumor mutational burden was available in 38 resected specimens with a median of 2.6 mutations per megabase (IQR: 1.0–4.4) and range from 0.5 to 22.6.