Evidence for the importance of BTNL8 in the development of enteropathy is highlighted not only by this study suggesting a role for BTNL8 in the resolution of gut inflammation but furthermore in a recent study, where BTNL8 was used as a marker for enteropathy in immunodeficiency, polyendocrinopathy, and enteropathy X-linked syndrome (IPEX) patients (Vazquez et al., 2022). This evidence concerns the gene BTNL8 and Abnormal intestine morphology.