Neutrophil gelatinase-associated lipocalin (NGAL) is a protein in neutrophil granules that is upregulated ten-fold within the first few hours of ischemic kidney injury in mouse models69 and can be detected in the kidney and urine within 3 hours of cisplatin administration.70 NGAL was recently cleared by the US Food and Drug Administration for AKI risk assessment in young patients aged 3 months to 21 years, and as such, we anticipate increasing utilization of this test to differentiate ATN from hemodynamic AKI. Here, LCN2 is linked to acute kidney injury.