ATM and viral infectious disease: Last, the NEP‐CRM1 interaction was reduced in H5N6 wild‐type virus infection but little affected in the H5N6‐DDD mutant virus infection in the ATM or CK2 knockout cells (Figure 6F), which not only demonstrates that S‐S‐S motif phosphorylation regulates NEP‐CRM1 interaction thereby affecting vRNP nuclear export and viral replication but also suggests a role of ATM and CK2 in NEP S‐S‐S phosphorylation.