Real-time PCR analysis indicated the mRNA expression of SEPP1, FGL2, KLRK1, and ABCA6 was downregulated in high risk NB samples and GAL was upregulated in the high risk NB samples, which were all consistent with the results of our bioinformatics analysis (p < 0.05, Figure 8). The gene discussed is FGL2; the disease is neuroblastoma.