KEGG pathways revealed that the DEGs were correlated with in immunity-related activities, including ‘Complement and coagulation cascades,’ ‘Primary immunodeficiency’ ‘Neutrophil extracellular trap formation, ‘T cell receptor signaling pathway,’ ‘PD-L1 expression and PD-1 checkpoint pathway in cancer’ and so on. Here, CD274 is linked to inborn error of immunity.