There are clinical studies demonstrated that IL-6 levels elevated in sputum from patients with COPD, and a time decay determination of predicted FEV1 percentage identified negatively correlated with lung function (Donaldson et al., 2005; Eickmeier et al., 2010; Grubek-Jaworska et al., 2012). Here, IL6 is linked to chronic obstructive pulmonary disease.