PDPN and neoplasm: As stated in Supplementary Table 2 and shown in Supplementary Figure 1A, tissue sections were stained with 31 metal-tagged antibodies detecting classical markers of tumor cells (Pan-Ck, Ck-7), pancreatic islets (peptide C); monocytic (CD45, CD68), polymorphonuclear (CD66b, MMP-9) and lymphoid (CD45, CD3, CD8, CD20) immune cells; cells composing the blood vessel wall, including vascular ECs (CD31, CD34), smooth muscle cells (CD146) and pericytes (CD146, αSMA); lymphatic ECs (CD31, podoplanin).