The status of different CDMs was compared in CD4+ T, CD8+ T, CD8+ Tex, Th17 and Treg between tumor tissues and NL controls, results showed that Th17 cells from tumor tissues manifested dramatically higher levels of alkaliptosis, whereas CD4+T and Treg from tumor tissues presented a decreased in apoptosisa (Figure 3C). The gene discussed is CD4; the disease is neoplasm.