IL4 and colorectal carcinoma: Interestingly, TLR7-treated CB-pDCs in co-cultures with the CRC tumor digest induced a broad range of cytokines and chemokines including the cytotoxicity-associated cytokine IFN-ɣ, as well as CCL5, CXCL9, and CXCL10, chemokines associated with T and NK cell recruitment and the pro-inflammatory cytokines IL-4, IL-5, and IL-17 (56–58).