Similarly, Im et al. (71) using 499 cases demonstrated a strong and statistically significant positive association between alcohol consumption instrumented by ALDH2-rs671 and ADH1B-rs1229984 and the risk of developing cirrhosis [HR = 2.30 (1.58–3.35); p = 1.5 × 10−5]. The gene discussed is ALDH2; the disease is Cirrhosis.