Lastly, a 23 kb deletion in chromosome 10 (SI Appendix, Fig. S3Ciii) lies in a locus rich with neurodevelopmental genes, including PPP3CB, which is downregulated in two in vivo ASD models(38, 39), CAMK2G, which is linked to neurodevelopmental disorders and associated with ASD, and P4HA1, which was found to be associated with ASD in a de novo risk score analysis(22). The gene discussed is CAMK2G; the disease is neurodevelopmental disorder.