CASP3 and Parkinsonism: Accordingly, the gestational exposure to smoking was associated with the upregulation of transcripts whose products act in the SNARE complex and are involved in vesicular transport, as well as transcripts of genes involved in Parkinson’s, Huntington’s, and prion-related diseases, such as Casp3, Psma6, and Nduvf1, placing MSDP as a potential not yet fully addressed environmental factor linked to the susceptibility or development of neurodegenerative disorders in offspring (57–59).