Analysis of the distribution of IL-8, POSTN, CHI3L1, SAA1, PLA2G2A, TREM1, IBSP, and MMP9 revealed that POSTN, CHI3L1, SAA1, and PLA2G2A were primarily expressed in cancer cells, with secondary expression observed in TAM (Fig. 2K). This evidence concerns the gene MMP9 and cancer.