CHSY1 and cancer: We found cancer cell signatures were enriched in “nervous system development”, “LICAM interactions”, “formation of tubulin folding”, “activation of AMPK downstream”, “cooperation of prefoldin and tric cct”, “Cyclin D associated events in G1”, “defective CHST3, CHST14 and CHSY1” and “dermatan sulfate bio-synthesis” pathways (Fig. 2I).