Analysis of the distribution of IL-8, POSTN, CHI3L1, SAA1, PLA2G2A, TREM1, IBSP, and MMP9 revealed that POSTN, CHI3L1, SAA1, and PLA2G2A were primarily expressed in cancer cells, with secondary expression observed in TAM (Fig. 2K). Here, CXCL8 is linked to cancer.